The Relief of Insomnia & The Chemical Joy of Rhodiola and Reactine

IMHO rhodiola and cetirizine beats diphenhydramine.

Rhodiola tweaks my opioid receptors, which are hedonism's tie in with the brain.

Cetirizine basically affects histamine receptors, but also cholinergic receptors, and consequently, the usual serotonin-dopamine-noradrenalin-adrenalin circus. it helps to have a benzhydryl head and a piperazine tail. The benzhydryl head tweaks the dopamine receptor, resulting in sleep. The piperazine tail tweaks serotonin receptors such that hypocretin is suppressed for at least 6 hours. Then it rises again, resulting in a fitful rest and no first-generation anti-histamine hangover.

However, wise users of anti-histamines should stop taking Reactine after using it for a full week to prevent the body from building tolerance.

Please note that vigorous morning exercise, not drinking caffeinated beverages and not arising from bed after retiring for the night is more effective in relieving insomnia.