The fact that MAO-A and MAO-B oxidizes both neurotransmitters and DMT so we don't go mad is not common knowledge.
Insomnia probably leads to neurotransmitters' levels changing which might lead to MAO not oxidizing DMT.
Hallucinations result, resulting in more stress.
At the root of this is cortisol, which reduces receptors from doing their job.
It is known that high levels of neurotransmitters leads to psychosis while low levels may explain depression.
However, anxiety may be a learned response to uncertainty.
DMT is naturally expressed in the brain, but is quickly metabolized, possibly by MAO.
IMHO it explains dreams.
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