According to the following link, bipolar depression, MS and schizophrenia may be due to human endogenous retrovirus (HERV-W). A compromised immune system affects monocytes (white blood cells) which activate the HERV-W virus.
As well, the XMRV has been associated with chronic fatigue syndrome and prostate cancer.
This leads me to speculate the following, which might be validated by medical evidence:
IMHO this may explain how mirtazapine works: its anti-histamine action affects the histamine part of inflammation. Inflammation results when mast cells are broken down by scavanger white blood cells, releasing histamine. How this may trigger HERV-W and XMRV is in part an immune reaction resulting from a complex combination of factors including stress and a viral infection, specifically from the herpes family.
Another side effect of antihistamines is sedation. Thus mirtazapine's antidepressant action may most likely be due to the thorough bed rest I get with daily dosage, which reduce my stress levels.
Originally posted: 11/13/2010 04:10:00 AM
Updated and edited: 12/05/2010 05:26:00 PM
For more information, see the following links:
http://en.wikipedia.org/wiki/Endogenous_retrovirus
http://bipolar-hotbrain.blogspot.com/2010/07/virus-herv-w-could-be-cause-of.html
The XMRV Retrovirus: http://www.youtube.com/watch?v=86OQJjLbHt0
Showing posts with label chronic fatigue syndrome. Show all posts
Showing posts with label chronic fatigue syndrome. Show all posts
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