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Showing posts with label painkiller. Show all posts
Showing posts with label painkiller. Show all posts

20101023

Is Mirtazapine Also a Pain Reliever?

It's been four months since starting mirtazapine, and I'm taking 30 mg a day.

Indeed mirtazapine is great for helping me sleep, yet one unexpected side effect is pain relief.

Yes, mirtazapine and mild exercise appears to reduce pain (headache and toothache). While I do not know the reason for the pain relief, it may be due to self-hypnosis - mirtazapine being a hypnotic - and improved metabolism of cortisol due to exercise.

Sedation is the usual effect of a hypnotic, and this drug isn't any different in that respect. However, being used to the sedative effects of mirtazapine, its hypnotic effect has help put to work the cognitive behavioral therapy that my therapist is patiently teaching me.

Also, this drug has helped me to learn from my mistakes.

Although it is possible I can easily learn from those mistakes on my own without medication, mirtazapine provides the calmness and reduced anxiety needed to function more fully both at home and in public.

IMHO each and every challenge while on mirtazapine makes it a "wonder drug" for me.

20090419

Using Robaxacet to Control Sore Shoulder

Due to a sore shoulder caused by a cumulative effect consisting of daily wear and tear over the past 20 years, my left shoulder sometimes gives me a lot of transient pain.

I even get transient aches and pains consistent with arthritis pain. It gets worse if I rest in bed.

However, a long day results in very little pain, including backache which is causal with aches in the arm - possibly due to a combination of poor posture and pinched nerves in the back.

Indeed, both wrists ache; both lower and upper arms on both sides ache; and so does the back.

However, I can sit or stand straight, and the pain is gone.

But, from time to time when I sleep on my left shoulder, it may sometimes ache; other times, no pain.

Lifting my left arm causes pain; but with the right arm, little pain.

As I said, physical activity relieves pain, possibly due to the effect of monamine oxidase on the breakdown of dopamine to adrenalin to noradrenalin to by-product of noradrenalin metabolism.

This same activity probably is why histamines break down.

At the same time, endorphin are produced to soothe any pains, and keep them at a dull ache.

Today I used a half dose of Robaxacet Extra Strength (400 mG metacarbamol, 500 mG acetaminophen) for a total dose of 200 mG methocarbamol and 250 mG acetaminophen.

My reasoning is that I don't need the sedative qualities of metacarbamol, but need the combination of acetaminophen and methocarbamol to deal with anticipated joint pain.

Given that both methocarbamol and acetaminophen have a 2 hours half-life, I know that by 4 PM, the pain may return.

At the same time I am taking a half-dose of Robaxacet, I am adding 400 mG of açai supplements for antioxidant effect, 500 mG of Eleutherococcus senticosus for adaptogenic optimization (helping to adapt to stress) and 2 G of wild salmon and fish oils, both to moderate brain function and keep my heart healthy.

As well, I've taken a dose of Vinpocetine (15 mG) to moderate cerebral function (memory and adaptation).

Hopefully this will keep my left shoulder to a dull ache, rather than the transient aches and pains outlined above.

This is still in keeping with my Less is More philosophy.

Update February 6, 2013 2351:
Roboxacet is OTC, which means it costs more than prescription for a welfare recipient using BC Pharmacare.

Since I'm on disability through the Income Assistance service, I greatly appreciate the help from all taxpayers in BC.

Currently I don't take anything mentioned above anymore. The only supplements I may take are for melatonin, calcium & magnesium and calcium, vitamins B6, D, & B-50 complex — regularly the Vitamin D and B-50 complex.

Of course, the medications I take are cyclobenzaprine (10 mg) and gabapentin (200 mg), which are the two safest medications for sleep (off-label but effective 90% of the time) and sleep architecture (promotion of deep sleep without benzodiazepine addiction risk).


YMMV

20070308

Marijuana effectively reduces pain

For the first time in nearly 20 years, a U.S. researcher has been able to publish the findings of a clinical study of therapeutic cannabis. The study, conducted by Dr. Donald Abrams of the University of California San Francisco medical school, found that HIV/AIDS patients suffering from neuropathic pain got twice as much relief from cannabis as compared to a control group.

The randomized placebo-controlled trial involved 50 patients who were randomly assigned to smoke either cannabis (3.56% tetrahydrocannabinol) or identical placebo cigarettes with the cannabinoids extracted three times daily for 5 days. Smoked cannabis reduced daily pain by 34% (median reduction; IQR = -71, -16). Greater than 30% reduction in pain was reported by 52% in the cannabis group and the first cannabis cigarette reduced chronic pain by a median of 72% vs. 15% with placebo.

Researchers concluded that smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from HIV-associated sensory neuropathy.

See http://neurology.org/cgi/content/abstract/68/7/515

This study suggests strongly that marijuana reduces chronic pain.